This is my first Bruinwalk review, and the reason I'm writing it is because I feel like more people should know about Prof Silkworth. This class was super interesting and hard as hell! but Prof Silkworth is so into biochem that it's hard not to catch his enthusiasm. Don't freak out if you bomb your first midterm. Even though he doesn't technically curve the class, he does scale your grades and offers a good amount of extra credit if the class collectively does poorly on a test. I studied my ass off, but was honestly floored when I got my final grade. A couple things:
GO to office hours!! I know everyone says that, but seriously, go to his office hours. Lecture can be rushed due to the sheer amount of info, but office hours let you actually take time to go over difficult topics.
Worry less about the problem sets and more about what he says to focus on in class. I started recording his lectures in case I missed something and it really helped, because he constantly drops hints about what to study. Focus on those problems in the sets.
Do get the textbook. An older version is fine, but it just really helps to get that extra clarification on mechanisms and additional diagrams. I'm pretty visual and the textbook has lots of that.
Finally, don't get too caught up with your grade. Just study hard and participate, and I think he recognizes that. You may be pleasantly surprised. Good luck!