Description: (Same as Pharmacology M205A.) Lecture, three hours; discussion, one hour. Enforced requisite: course 153A with grade of C- or better. Introduction to chemical biology. Topics include computational chemical biology, utility of synthesis in biochemical research, peptidomimetics, designed reagents for cellular imaging, natural product biosynthesis, protein engineering and directed evolution, cell biology of metal ions, imaging metal ions in cells, metal-containing drugs. Concurrently scheduled with course C105. Letter grading.

Units: 4.0