BIOENGR C105
Engineering of Bioconjugates
Description: Lecture, four hours; discussion, one hour; outside study, seven hours. Enforced requisites: Chemistry 20A, 20B, 20L. Highly recommended: one organic chemistry course. Bioconjugate chemistry is science of coupling biomolecules for wide range of applications. Oligonucleotides may be coupled to one surface in gene chip, or one protein may be coupled to one polymer to enhance its stability in serum. Wide variety of bioconjugates are used in delivery of pharmaceuticals, in sensors, in medical diagnostics, and in tissue engineering. Basic concepts of chemical ligation, including choice and design of conjugate linkers depending on type of biomolecule and desired application, such as degradable versus nondegradable linkers. Presentation and discussion of design and synthesis of synthetic bioconjugates for some sample applications. Concurrently scheduled with course C205. Letter grading.
Units: 4.0
Units: 4.0
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Most Helpful Review
Fall 2023 - He is a pretty chill professor and the class is a pretty chill class. I enjoyed the content and at the end of the day, I feel like I learned valuable information. His lectures are relatively dense and his slides can be a bit messy and hard to read (as they are handwritten) so it is really important to not skip class. There were no recordings in my class so if you can it might be helpful to record audio (and even video). The class had 4 HW assignments, 4 quizzes, 1 final. He does give practice quiz. I recommend summarizing the lectures for yourself after the class as he can cover lots of reactions which can pile up very fast and easily, however since the class builds on it self a lot studying for the final was pretty easy since it you basically have to know everything by the last quiz anyway. The biggest problem I had with this class was that there were just not enough practice problems and so it would have been nice if we had more practice problems. Our TA was amazing and really helpful in explaining the concepts and also graded very fair. This class is not the easiest elective, but it isn't too bad either. However, it is best to take this class after you have taken all the organic chemistry classes as there is lots of organic chemistry. Although he teaches you everything you need to know it will be ALOT easier if you already know it.
Fall 2023 - He is a pretty chill professor and the class is a pretty chill class. I enjoyed the content and at the end of the day, I feel like I learned valuable information. His lectures are relatively dense and his slides can be a bit messy and hard to read (as they are handwritten) so it is really important to not skip class. There were no recordings in my class so if you can it might be helpful to record audio (and even video). The class had 4 HW assignments, 4 quizzes, 1 final. He does give practice quiz. I recommend summarizing the lectures for yourself after the class as he can cover lots of reactions which can pile up very fast and easily, however since the class builds on it self a lot studying for the final was pretty easy since it you basically have to know everything by the last quiz anyway. The biggest problem I had with this class was that there were just not enough practice problems and so it would have been nice if we had more practice problems. Our TA was amazing and really helpful in explaining the concepts and also graded very fair. This class is not the easiest elective, but it isn't too bad either. However, it is best to take this class after you have taken all the organic chemistry classes as there is lots of organic chemistry. Although he teaches you everything you need to know it will be ALOT easier if you already know it.
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